BOOK

Factors Influencing Myocardial Contractility

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This work examines the various physiological, biochemical, and pharmacological factors that influence myocardial contractility, defined as the intrinsic ability of cardiac muscle fibers to contract independently of loading conditions. The authors analyze the role of ionic movements—particularly calcium—in excitation-contraction coupling, and evaluate how autonomic nervous system activity modulates cardiac performance.
The text further explores the effects of pharmacologic agents, including cardiac glycosides and other inotropic substances, on myocardial force generation. Additional factors such as myocardial oxygen supply, metabolic state, and pathological conditions like ischemia and heart failure are discussed in relation to their impact on contractile function.
Drawing on experimental models and clinical observations available at the time, the book contributes to the foundational understanding of cardiac mechanics and serves as an important early reference in cardiovascular physiology and pharmacology.

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Availability

Detail Information

Series Title

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Call Number

591,41 F137

Publisher

New York and London : Academic Press., 1967

Collation

-

Language

English

ISBN/ISSN

Not available

Classification

591,41

Content Type

text

Media Type

unmediated

Carrier Type

-

Edition

1st

Subject(s)

Cardiac physiology Myocardial contractility Cardio

Specific Detail Info

-

Statement of Responsibility

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Other version/related

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