BOOK
The Chemistry and Biochemistry of the Sulfhydryl Group in Amino Acids, Peptides and Proteins
This monograph provides a comprehensive and systematic examination of the chemical and biochemical properties of sulfhydryl (–SH) groups in amino acids, peptides, and proteins. It focuses primarily on cysteine and related thiol-containing compounds, discussing their reactivity, oxidation–reduction behavior, nucleophilic properties, and role in protein structure and function. The book critically analyzes sulfhydryl–disulfide interconversions, interactions with metals and reagents, and the involvement of thiol groups in enzyme catalysis, protein stability, and biological regulation. Intended for biochemists, protein chemists, and advanced researchers, the volume compiles experimental data and theoretical interpretations that were foundational to sulfur chemistry in biological systems at the time of publication.
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