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Solid-Phase Synthesis and Combinatorial Technologies

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This work explores the principles and applications of solid-phase synthesis and combinatorial chemistry as powerful tools for the rapid construction of diverse chemical libraries. Beginning with the foundational concepts of solid-phase organic synthesis (SPOS), including resin selection, linker chemistry, and reaction optimization, the text advances to modern techniques used in peptide, oligonucleotide, and small molecule synthesis. It also highlights the role of combinatorial technologies in accelerating drug discovery and materials development through high-throughput screening and parallel synthesis. Emphasis is placed on automation, efficiency, and the strategic design of compound libraries. This resource serves as a critical guide for researchers in medicinal chemistry, chemical biology, and related disciplines.

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Detail Information

Series Title

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Call Number

547,2 S475

Publisher

New York : JOHN WILEY&SONS., 2000

Collation

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Language

English

ISBN/ISSN

0-471-33195-3

Classification

NONE

Content Type

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Media Type

unmediated

Carrier Type

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Edition

1st edition

Subject(s)

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Specific Detail Info

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Statement of Responsibility

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